Neuroservice USA

in vitro Electrophysiology & Calcium Imaging

Based in San Diego, California, Neuroservice USA is the child company of Neuroservice and benefits from the 15 years of experience of Neuroservice in providing pharmacological assays based on electrophysiological recordings, and focuses on human cells recordings (human iPSC-derived neurons and human DRG sensory neurons) as well as non human in vitro ephy recordings.

Neuroservice USA functions on the same collaborative model: our scientific team establishes strong links with your projects leader, and we share continuously robust functional data to support decision making during any phase of CNS/PAIN drug discovery research programs.

CNS & PNS Pharmacology / Emectrophysiology

Thanks to a complete master of Patch-clamp & Calcium Imaging techniques, Neuroservice USA investigates your compound’s effects on neuronal networks and single neurons, specifically iPSC neurons derived from human donors (healthy or patients).

Depending on the pathology targeted by your compound, Neuroservice USA researchers will propose protocols tailored to your needs and reveal your compound properties: pharmacological properties, target(s), Mechanism(s) of Action and Safety issues.

In addition, Neuroservice USA proposes electrophysiological characterization services of iPSC-derived neurons (proprietary or commercial cell lines).

Patch Clamp

Neuroservice is a world-renowned leader in patch clamp electrophysiology.

Patch Clamp allows in vitro evaluation of compounds under the most physiologically relevant conditions.


Calcium Imaging

Calcium Imaging can either measure individual cell or global neuronal network Ca+ dynamics at a very high resolution. Calcium Imaging analysis tools allow to circle regions of interest in the studied neuronal culture, so that AP firing can be measured locally.