Customized Solutions

CUSTOMIZE OUR ASSAYS

YOUR PROGRAM REQUIRES SLICE ELECTROPHYSIOLOGY FOR CRITICAL LEAD SELECTION /MECHANISM OF ACTION STUDIES?

Thanks to more than 500 studies performed, Neuroservice can design and perform any kind of CNS electrophysiological assay.

Together we can undertake a Design-To-Cost process to reach a customized study plan addressing your scientific questions and fitting your budget and timelines.

Once we agree on the study plan, we can set up a contract to complete the experiments and provide you with the data in short delays.

WITH OUR ASSAYS, YOU CAN INVESTIGATE:

MOLECULAR EFFECTS UNDER REAL PHYSIOLOGICAL CONDITIONS
DOSE-RESPONSE OR DOSE-INHIBITION PROTOCOLS
CHARACTERIZATION OF ALLOSTERIC MODULATORS
DRUG-DRUG
INTERACTIONS
EFFECTS ON
SYNAPTIC PLASTICITY
EFFECTS ON
SYNAPTIC TRANSMISSION


We can record from slices prepared from Wild Type (WT) or Transgenic (Tg) rodents*

  • Tg-Mouse/Tg-Rat deficit (or gain) of function versus WT
  • Physiological characterizations of Tg-Mouse/Tg-Rat versus WT
  • Drug candidate evaluation in a rodent disease model
FASTER
2 WEEKS
LESS ANIMALS REQUIRED
10 WT / 10 TG
LESS COMPOUNDS
REQUIRED

*The Tg rodents are supplied from customers or commercial providers

OUR PORTFOLIO OF STUDIES

Coming soon

Assay contract

“FEE FOR SERVICE” CONTRACT FOR CUSTOMIZED ASSAYS.

The Fee For Service contract is based on a Study Plan:

  • Given number of validated slices (MEA) / neurons (PATCH) to record from
  • Study timeline
  • Study cost

Our model is to work as your remote laboratory. During the course of the study:

  • You have access in real time to the study workflow as well as to the raw data completed by the lab
  • You can interact at any time with our scientific team to discuss, adapt, modify, re-orient the study Plan. The contract will be updated in parallel in accordance with agreed amendments
  • You benefit from our expertise in Neurophysiology and Neuropharmacology to analyze and interpret the raw data

Study report samples

MEA – Characterization of LTP profiles in WT & KO mice May

Download

PATCH CLAMP EFFECT OF COMPOUNDS ON GLYCINE EVOKED CURRENTS

Download