Cloned Channels and Receptors

Cloned channels and receptor

We can perform recordings on:

  • Stable cell lines
  • Transfected cells
Patch clamp recording on cloned channels and receptors

PROTOCOLS AVAILABLE

PATCH CLAMP
Passive membrane properties

– Input resistance
– Membrane capacitance
– Access resistance
– Resting Membrane Potential (RMP)
PATCH CLAMP
Active membrane properties

– Rheobase
– Spike threshold
– Spike Amplitude
– Firing frequency
– Voltage-gated ion channels
– Ligand gated ion channels
– GPCR modultation
PATCH CLAMP
Synaptic transmission and plasticity

– Evoked responses
– Miniature currents
– Spontaneous currents
HD MEA
– Spontaneous firing activity
– Short term synaptic plasticity
– Long term synaptic plasticity

CALCIUM IMAGING

– Firing activity on small neuronal subpopulation

SAMPLE DATA