Safety & Toxicology Profiling
NEUROSERVICE provides an innovative screening platform utilizing electrophysiological slice recordings to detect the pro-convulsive properties of compounds and to investigate their acute or chronic toxicity on basal synaptic transmission/plasticity.
Slices for chronic toxicity studies are prepared from vehicle-treated and compound-treated animals.
The recordings are performed in acute brain slices from rodents (mice or rats) with the Multi-Electrode Array (MEA) technique.
This innovative in vitro recording approach provides a very precise response and a more rapid turnaround than the IRWIN battery.
2 PACKAGES ARE AVAILABLE FOR THIS PLATFORM:
- NeuroSafety Package: to address a number of primary functional aspects of neuronal excitability and neurotransmission
The NEUROSAFETY PACKAGE
click to download the NEUROSAFETY PACKAGE :
the right & the fast answer.
- Pro-convulsive package: to detect the Pro-convulsive properties of compounds