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Patch-Clamp

NEUROSERVICE provides a wide range of tests with the Patch-Clamp technique which delivers the highest resolution for electrophysiological recordings of single channel thanks to the different recording configurations :

  • Whole-cell
  • Perforated-patch
  • Cell-attached
  • Outside-out
  • Single Channel

The Patch-clamp technique offered by NEUROSERVICE allows recording on acute Brain and Spinal Cord slices to give you the accurate results expected.


NEUROSERVICE could answer very precise physiological and pharmacological questions with this technique, clearly dedicated to the understanding of mechanisms of action.

 

 

Structure

Spinal Cord without roots

Spinal Cord with roots

Hippocampus

Ventral Tegmental Area

Locus Coeruleus

Dorsal Raphe

Periaqueductal Gray Matter

Cortical slices (temporal cortex)

Cortico-striatal slices

Striatum

Substantia Nigra

Amygdala

Cerebellum slices

Protocol

Firing Activity

Spontaneous Postsynaptic Currents

Miniature Postsynaptic Currents

Evoked Postsynaptic Currents

Postsynaptic Responses

Paired-Pulse Protocols

Long-Term Potentiation

Long-Term Depression

Pharmacology of Intracellular Pathways

Dose-Response Curves

Root Stimulation of Spinal Cord

Field Potentials

 

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