Gamma Oscillations: a new translational biomarker to predict in vivo oscillatory activity in an in vitro model
Neuronal rhythms are disordered in schizophrenia, epilepsy, autism, ADHD, Alzheimer’s Disease and Parkinson Disease, among others. Oscillations in the gamma frequency range are thought to be responsible for information transfer and integration between different brain areas. With Neuroservice’s “GOS SET” package based on electrophysiological slice recordings with Multi-Electrode Array, you can investigate the effects of your compounds at the neuronal network level. This set of in vitro assays provides a direct efficacy readout for your compound on a complex neuronal network, as well as a translational biomarker for further in vitro/in vivo investigations.
A session poster was held in Neuroscience, the annual meeting of the Society for Neuroscience (SfN), in Washington on November: “In Vitro Recordings of Gamma Oscillations with the Multi-Electrode Array for the Characterization of CNS Drugs”.
Interested in this presentation? Discover Neuroservice’s poster