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Who are they?Who are they?

We provide our clients with different solutions in

Lead Selection & Optimization
Lead Selection & Optimization

NEUROSERVICE provides a wide range of electrophysiological assays to support the lead compound and optimization during the R&D phases of CNS and Pain programs.

  • Validation of multiple series of compounds with real physiological data.
  • Determination of Dose-Response or Dose-Inhibition profiles for reference & test compounds.
  • Mid-throughput Screening of series of compounds under physiological conditions.
  • Precise determination of lead pharmacological profiles for selection and optimization.
Mechanism Of Action
Mechanism Of Action

NEUROSERVICE provides a wide range of electrophysiological assays to validate target(s) and to understand the Mechanism(s) Of Action of lead compounds.

  • Molecular effects under real physiological conditions
  • Dose-Response or Dose-Inhibition Protocols
  • Characterization of Allosteric Modulators
  • Drug-drug interactions
  • Effects on Synaptic Transmission
  • Effects on Synaptic Plasticity
Safety and Toxicology Profiling
Safety and Toxicology Profiling

NEUROSERVICE provides an innovative screening platform utilizing electrophysiological slice recordings to detect the pro-convulsive properties of compounds and to investigate their acute or chronic toxicity on basal synaptic transmission/plasticity. Slices for chronic toxicity studies are prepared from vehicle-treated and compound-treated animals.

Their fields of activityTheir fields of activity

multi-electrode array lab about clients
Cns & pain drug discovery

Neuroservice supports pharmaceutical and biotech companies at each step of the R&D drug development process providing high quality electrophysiological data with rapid turn around. NEUROSERVICE aims to be the long term partner for electrophysiological data to empower internal decision-making for research programs in the CNS & Pain fields.

multi-electrode array lab about clients
SAFETY AND TOXICOLOGY

Neuroservice provides an innovative screening platform utilizing electrophysiological slice recordings to detect the pro-convulsive properties of compounds and to investigate their acute or chronic toxicity on basal synaptic transmission/plasticity.

multi-electrode array lab about clients
HEALTH FOUNDATIONS

The core activity of Foundations is to accelerate the Drug Development process for research programs in the area of CNS & PAIN disorders within collaborative networks (Pharma organizations, Biotechs, CROs, Academics…).
Electrophysiological-based assays (rodent brain & spinal cord acute slices and cultured neurons) are very critical in evaluating the Neurophysiological, Neuropharmacological and Neurotoxicological effects of drugs targeted for CNS disorders.

multi-electrode array lab about clients
NUTRITION & HEALTH

Neuroservice supports Pharmaceutical companies focusing on nutritional and general health research programs that target the Central Nervous System.
We also offer scientific expertise for Food & Ingredient Industries investing in innovate research programs that aim to achieve CNS-related benefits. The in vitro electrophysiologically-based assays are a key solution to evaluate and demonstrate a compound’s benefit on key CNS functions.
Neuroservice is a real partner for innovation in nutrition & health dedicated to the CNS.

The best way to evaluate Neuroservice is to test one of your reference compounds!

TestimonialsTestimonials

FRANK MENNITI PHD, CHIEF SCIENTIFIC OFFICER, MNEMOSYNE PHARMA
Frank Menniti
PhD, Chief Scientific Officer
Mnemosyne Pharma
Frank Menniti, PhD, Chief Scientific Officer
Mnemosyne Pharma

“I’ve worked with Neuroservice on several projects, at two companies. The quality of the work and data are excellent. More significantly, I have very much appreciated the collaborative nature of my interactions with Neuroservice. They’ve helped me ask research questions, not simply generate data. I’ve taken great advantage of their technical as well as scientific expertise. They have been a valued component of my project teams.”

jacinthe gingras AMGEN
Jacinthe Gingras
PhD, Principal Investigator
Amgen
Jacinthe Gingras, PhD, Principal Investigator
Amgen

“Professionalism, high quality data and fast turn-around time only begin to describe the Neuroservice team. What a pleasure it is to work with such a qualified and flexible group.”

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